WP Live CSS Editor is a new plugin that is actually a port from a Drupal module called Live CSS. It allows you to preview realtime CSS changes and then save the CSS back while keeping dated backups. You can edit any and all CSS files that are loaded in the page, provided they have write permission and you are looged in.

If you’re going to be doing a lot of CSS editing on your WordPress site, then this plugin might be just the ticket for helping you to be more efficient. Download WP Live CSS Editor for free from the WordPress plugin repository.
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Damn this looks sweet! Thanks for posting. Gonna try it out this weekend. I guess this makes sense as the next step beyond FireBug. Ahhh another time saver for devs…
Thanks,
John
Very nice, this looks like it could be very useful! Thanks for sharing
Just what I need! Thank you!
Works like a Charm! thanks again Sarah.
AaaaaaaaaweSooooooommmmmmmmme
Can’t think of any beta way to say it
Is there a real time PHP editor available?
This is probably the BEST plug-in I’ve ever used. I can’t tell you how much time this saves me from editing a CSS file that is a mile long – and I can do it in real time and instantly save. Anyone who does wild development in WP and relies heavily on CSS files – get this plug-in!
I’m sure this was an awesome plugin in it’s time, but for anyone planning on using this in 2013, THIS PLUGIN WILL CORRUPT YOUR CSS. It’s very incompatible with the latest version of WordPress. For some reason it added a ton of “\” symbols in all my webfont urls, rendering them useless. And once it saves it becomes permanent. You’ll have to go into your css file and manually delete all the “/” it adds in. Huge pain if you use a lot of webfonts.